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Professor David Wyllie is a leading researcher at the Centre for Discovery Brain Sciences with a focus on neurotransmitter action in central neurons, particularly studying ligand-gated ion channels (LGICs). He investigates the role of N-methyl-D-aspartate receptors (NMDARs) in synaptic transmission and their crucial functions in learning and memory. His lab’s research has contributed significantly to the understanding of NMDAR subtypes' structure-function properties and their roles in neurological disorders such as Alzheimer’s, Parkinson’s, and schizophrenia. Wyllie's work encompasses using pre-clinical models to study neurodevelopmental disorders and assessing the electrophysiological profiles of induced pluripotent stem cells. He aims to develop integrated approaches to understand synaptic function and develop treatments for neurodegenerative diseases. His ongoing projects are supported by various research grants and collaborations with esteemed colleagues across institutions.
Institute of Neuroscience and Cardiovascular Research • University of Edinburgh
Overseeing research operations and collaborations within the institute.
Journal of Physiology •
Editing and reviewing submissions for the journal.
Centre for Discovery Brain Sciences • University of Edinburgh
Leading research initiatives and projects in neuroscience.
Journal of Physiology •
Involved in the peer-review process for submitted articles.
Centre for Integrative Physiology •
Managed the centre's research and academic programs.
Department of Pharmacology, University College London •
Conducted independent research on pharmacology-related topics.
Department of Marketing