Professor Dr. Debs Brotherton

Biography

Debs Brotherton is an Assistant Professor with a focus on biochemistry, particularly on understanding how proteins interact and respond to cellular signals. She employs a range of biological techniques to study the molecular mechanisms of protein interactions, examining how changes in protein structure can affect their functions. Her research emphasizes the development of targeted drugs to enhance or inhibit protein behavior, particularly in the context of membrane proteins. Currently, her work involves high-resolution structural analysis of gated ion channels and secondary transporters using advanced techniques like Cryo-Electron Microscopy and X-ray crystallography. Debs is also part of a team investigating carbon dioxide-sensitive proteins, bridging structural biology with physiological studies to understand the impact of genetic mutations on protein function within a cellular environment. Before her current position, she completed her undergraduate studies in Biochemistry at the University of Bath and a PhD at Clare College, Cambridge, where she focused on cyclin-dependent kinases. Her experience spans the biotechnology sector, including work on anti-cancer and anti-inflammatory drugs.

Research Interests

Experience