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Dr. Defne Amado is an Assistant Professor of Neurology at the Perelman School of Medicine at the University of Pennsylvania. She is a physician-scientist whose research focuses on gene therapy-based approaches for understanding and developing treatments for neurodegenerative diseases. Her clinical expertise includes managing amyotrophic lateral sclerosis (ALS) at the Penn Comprehensive ALS Center, where she treats patients and participates in a general neuromuscular clinic focused on inherited and acquired neuropathies. Dr. Amado's research interests incorporate advanced gene therapy techniques, including using adeno-associated viral (AAV) vectors for gene silencing and addressing the pathobiology of diseases such as ALS, frontotemporal dementia, and spinocerebellar ataxia. Her lab is committed to fostering an inclusive and diverse environment, enabling trainees to thrive in their research pursuits. Amado completed her MD and PhD at the Perelman School of Medicine and undertook extensive postdoctoral training in neurodegenerative disease and gene therapy.
Perelman School of Medicine at the University of Pennsylvania • Philadelphia, PA
Conducts research and teaches in the Department of Neurology.
Hospital University of Pennsylvania • Philadelphia, PA
Completed internship in Internal Medicine.
Hospital University of Pennsylvania • Philadelphia, PA
Completed residency in Neurology.
University of Pennsylvania • Philadelphia, PA
Fellowship in Neuromuscular Disorders.
University of Pennsylvania • Philadelphia, PA
Conducted research in Neurodegenerative Disease.
University of Pennsylvania • Philadelphia, PA
Conducted research in Gene Therapy.
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