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Dejian Ren is an Assistant Professor at the University of Pennsylvania in the Department of Biology. He received his Ph.D. in Physiology Biophysics from SUNY Buffalo in 1997. His research focuses on understanding the molecular mechanisms that regulate neuronal excitability and animal physiology, particularly through the roles of extracellular ions and peptide neurotransmitters. Ren employs a range of biological techniques including electrophysiology, molecular biology, and live cell imaging in his work. He investigates how changes in calcium ion concentrations impact neuronal signaling and how neuropeptides can regulate the electrical properties of neurons across various brain regions. His lab is particularly interested in rhythm generation and modulation, studying both long-period rhythms such as circadian cycles and shorter rhythms involved in locomotion and other physiological processes. Ren has published extensively, with notable works exploring ion channels' roles in neuronal excitability and rhythmic behaviors. He aims to uncover the complex signaling events that contribute to intrinsic neuronal properties across physiological and pathophysiological conditions.
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