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Dejian Ren is an Assistant Professor in the Department of Biology at the University of Pennsylvania. His research focuses on the molecular mechanisms underlying neuronal excitability and animal physiology, particularly the role of extracellular ions and peptide neurotransmitters. Ren utilizes a variety of techniques including electrophysiology, molecular biology, and live cell imaging to study how neuronal networks function and how ion channels and G-protein coupled receptors affect signaling within neurons. His lab investigates significant changes in extracellular calcium concentrations and the physiological and pathological conditions such as seizures and brain ischemia that arise from these changes. Additionally, Ren's work explores how neuropeptides regulate physiological processes like feeding, pain sensation, and arousal. He is known for his contributions to understanding the activation mechanisms of ion channels and the generation of rhythmic behaviors, linking molecular mechanisms to cellular and system-level physiological outputs.
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