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Dennis Trumble uses multiscale computational models to develop implantable devices for cardiac assist purposes. His work aims to produce a unique muscle-powered heart assist device for long-term use, marking a major advancement in the treatment of congestive heart failure. Professor Trumble holds appointments at the Biomedical Engineering Center and Neural Basis of Cognition. His book, 'The Way Science,' was named a AAAS/SB&F Book in 2014 in the category of Ethics. He is a recipient of the Idea Foundry Transformation Fellowship and the DMDC Top Presentation Award. Dr. Trumble’s research has been supported by the NIH, Pittsburgh Foundation, Innovation Works, Whitaker Foundation, and Allegheny-Singer Research Institute. His work on muscle-powered implants has been featured in Science Magazine, Scientific American, Popular Science, Men’s Health, and the Pittsburgh Post-Gazette. The Trumble lab focuses on developing innovative approaches for long-term mechanical circulatory support. Primary research activities center on the design, manufacture, and testing of muscle-powered, non-blood contacting cardiac assist devices to avoid major limitations of existing blood pump technologies used to support failing hearts for extended periods. In this regard, he is currently working on a ‘soft robotic sleeve’ designed to squeeze and twist the ventricles, using multiscale computer simulations to identify effective patterns for direct cardiac compression and torsion in diseased hearts. This new approach to circulatory support aims to provide a versatile means to manipulate the mechanical environment of the heart for rehabilitation, reducing recovery time and avoiding serious risks associated with blood-contacting surfaces and percutaneous drivelines.
Admission is extremely competitive with no strict GPA cut-offs; holistic review is used.