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Donald T. Fox serves as a Professor in the Department of Pharmacology and Cancer Biology at the Duke Cancer Institute. His research is centered on genomic extremes and their implications for organ development and repair. Fox's work investigates how specific features of genomes can be altered to exploit extreme variations, focusing particularly on polyploidy and codon usage bias. His laboratory has established models using Drosophila to explore the roles that these genomic variations play in defining specialized cell and tissue functions. By examining polyploidy, Fox seeks to understand the consequences of whole genome duplication on the transcriptome, proteome, and metabolome, particularly in contexts of organ development and repair. Furthermore, he investigates codon usage bias and its effects on mRNA translation and tissue-specific differentiation. Fox holds a B.S. from the College of William and Mary and a Ph.D. from the University of North Carolina at Chapel Hill.
Department of Biomedical Engineering (MS program)