Dr. Dong Er Zhang

Biography

Dr. Dong-Er Zhang's research focuses on the molecular basis of cancer development, progression, and treatment. His laboratory employs genomic, proteomic, and cell biology approaches to address these critical questions and explore the therapeutic potentials based on newly acquired knowledge. A major ongoing project in Dr. Zhang's lab investigates the role of the transcription factor AML1 (RUNX1) fusion protein AML1-ETO in blood stem cells. Additionally, the lab studies the function of the ubiquitin-like modifier ISG15 and the related protease USP18 (UBP43) in the context of cancer immunology. Dr. Zhang received his BS in Biochemistry from Peking University in China and was selected to enter the graduate school in the United States through the CUSBEA program, leading to a PhD in Biochemistry from the University of Houston. He has held positions as a Postdoctoral Scholar and Instructor at the University of Texas, and later as an Instructor and Assistant Professor at Harvard Medical School. In 1999, Dr. Zhang joined the Scripps Research Institute as an Associate Professor and was subsequently promoted to Full Professor at UCSD. He is actively involved in multiple international grant review committees and contributes to the organization of scientific conferences. Dr. Zhang has been recognized as a Leukemia Lymphoma Society Scholar from 1998 to 2003 and received the prestigious Stolhman Scholar Award from the same society, as well as being elected as a fellow of the American Association for the Advancement of Science.

Research Interests

Experience