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Donna L. George is an Emeritus Associate Professor in the Department of Genetics at the Perelman School of Medicine, University of Pennsylvania. Her research is centered on molecular pathways governing the control of cellular growth and the initiation and progression of human cancers. She focuses on the p53 tumor suppressor gene, which plays a critical role in mediating apoptosis and protecting against malignant transformation. Moreover, her work investigates the direct role of p53 in mitochondrial apoptosis, uncovering interactions between p53 and mitochondrial proteins, such as BAK, that regulate cell death pathways. In addition to her work on p53, Dr. George studies the multifunctional molecular chaperone HSP70, investigating its role in cancer cell survival amid metabolic stress and its potential as a therapeutic target.
University of Pennsylvania School of Medicine • Philadelphia, PA
Oversaw the Master's programs and contributed to academic and administrative functions within the School of Medicine.
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