Dr. Doris Stoffers

Biography

Doris Stoffers is a prominent researcher in the field of endocrinology and metabolism focused on understanding the molecular pathways regulating pancreatic islet beta cells responsible for insulin production. She leads a biomedical research group that includes postdoctoral fellows, MD-PhD students, and undergraduates, all dedicated to exploring the regulatory networks that govern beta cell development and function. Her work extensively investigates the role of transcription factors, particularly Pdx1, in pancreas specification and the pathophysiology of diabetes mellitus. Dr. Stoffers' laboratory has also identified critical partnerships between various proteins that influence beta cell survival under stress conditions. By employing genomic and proteomic approaches, her research aims to elucidate the mechanisms of beta cell differentiation and maintenance. The ongoing projects within her lab encompass a collaborative effort to define the roles of newly discovered targets pertaining to beta cell function, with a prominent emphasis on the regulation of gene expression and the implications of these molecular interactions in the context of diabetes.

Research Interests

Experience