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Dr. Dorothy Wai completed her PhD at the University of Sydney in 2017, where she utilized NMR biophysical techniques to characterize protein-protein and protein-RNA interactions that regulate mammalian gene expression. She has significant experience in fragment-based drug discovery projects specifically targeting proteins related to type 2 diabetes and graft-versus-host disease, employing her expertise in molecular biology, protein biochemistry, and structural biology. Currently, her research is centered on the development of peptides to inhibit the potassium channel K V 1.3, which is being studied as a novel molecular target for neurodegenerative diseases. This work aims to create therapeutic leads that possess improved brain permeability and pharmacokinetic properties. Dr. Wai's efforts have successfully attracted competitive funding, which is essential for expanding the limited therapeutic options currently available for individuals suffering from neurodegenerative disorders.
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