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Douglas Smith is a Professor in the Department of Physics at the University of California, San Diego. He received his Ph.D. from Stanford University in 1999, focusing on the study of mechanical manipulation of single DNA molecules. His research interests include viral DNA packaging, particularly of bacteriophages such as phi29, lambda, and T4. He investigates the functions of ATP-dependent molecular motors and the dynamics of single polymers in terms of polymer physics, DNA properties, and rheology. Smith’s work extends to the assembly and structure of chromatin, enzyme-mediated DNA looping, and the functionality of restriction endonucleases. He has published extensively on the velocity control of DNA translocation, knotting in biophysics, and the dynamics of DNA packaging motors, contributing significantly to the understanding of high forces and motor processivity in DNA packaging systems.
Administered by the Scripps Institution of Oceanography. Curricular groups include Climate-Ocean-Atmosphere (COAP), Geosciences (GEO), and Ocean Biosciences (OBP).