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Edward Doherty studies immune system dysregulation and how immune response leads to autoimmunity, focusing on the role of MIF receptor-expressing T cells in health and disease. His research involves studying MIF cytokine activity, particularly in high concentrations found at inflammation sites, such as rheumatoid arthritis (RA) joints. Doherty's work elucidates the role of the novel MIF receptor (CD74) expressing T cells identified in mouse models of RA. Additionally, he has investigated the immune response to mRNA vaccines during the COVID-19 pandemic, particularly B cell antibody production and the effects of self-amplifying RNA vaccines. He is actively involved in collaborative efforts to better understand these complex immune responses.
Administered via the Graduate School of Arts and Sciences (GSAS). GRE General is optional for PhD.