Dr. Edward Hawrot

Biography

Edward Hawrot is the Alva O. Way Professor in the Department of Molecular Biology, Cell Biology, and Biochemistry at Brown University. He received his Ph.D. in Biochemistry from Harvard University and completed a postdoctoral fellowship in Biological Chemistry at Harvard Medical School. After spending ten years on the faculty at Yale University School of Medicine in the Department of Pharmacology, he relocated to Brown University in 1990, initially serving as the Chair of the Section of Molecular Pharmacology in the Division of Biology and Medicine. His research focuses on understanding the structure and function of nicotinic acetylcholine receptors, particularly their interactions with neurotoxins. His work aims to elucidate the fundamental structure-function relationships of these receptors, using techniques such as homologous recombination to create knock-in mouse models for studying alpha3-containing neuronal nicotinic receptors. Through his innovative research, he has significantly contributed to the understanding of drug-receptor interactions and the molecular basis of specificity for these receptors, which are crucial for synaptic transmission at the neuromuscular junction and in the central nervous system.

Research Interests

Experience