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Elaine Elion is a Professor in the Department of Biological Chemistry and Molecular Pharmacology at Harvard University. Her research group studies eukaryotic signal transduction, focusing on how external stimuli control proliferation, differentiation, and homeostasis. Her work has centered on defining the function of mitogen-activated protein kinase (MAPK) cascades in vivo. MAPK cascades form the core of numerous eukaryotic signal transduction pathways that control growth, differentiation, and survival. Misregulation of MAPK cascades is associated with a variety of diseases, including cancer. The group employs yeast model systems alongside genetic, biochemical, and cell biological approaches to further understand these processes.
Administered by the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences (GSAS).