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Elazer Edelman leads the Edelman Lab at the Harvard-MIT Biomedical Engineering Center, a collaborative research environment that brings together clinicians, engineers, and scientists from academia and industry to create translatable solutions for clinically relevant problems. The lab focuses on several key areas, including continuum mechanics, digital signal processing, molecular biology, and polymeric controlled release technology. Significant projects include investigating the interplay of mechanical support devices with native physiology and cellular molecular mechanisms, aimed at transforming stable coronary artery disease into unstable coronary syndromes. The lab also explores tissue-engineered cells to deliver growth factors and growth inhibitors for potential treatments of accelerated arterial disease following angioplasty and bypass surgery. Furthermore, Edelman Lab holds patents for various innovative medical solutions, including drug-delivery devices and mechanical circulatory support approaches, contributing to advancements in tissue engineering and novel drug formulations.