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Elena Posse de Chaves is a Professor in the Department of Pharmacology at the University of Alberta, with a focus on understanding the role of lipids and lipoproteins in neurodegeneration, particularly in Alzheimer's disease. Her lab employs biochemical and cell biological approaches, collaborating with functional studies in animal models to investigate the regulatory mechanisms involved in neurodegenerative processes. Notably, her research explores the connection between cholesterol metabolism and Alzheimer's disease pathology, highlighting how oligomeric amyloid beta peptide disrupts lipid pathways and protein prenylation, crucial for normal neuronal function. Through her work, she aims to develop therapeutic strategies to mitigate the progression of Alzheimer's disease and other associated health problems. Elena's work has been published in notable scientific journals, demonstrating her expertise in the intricate relationships between cholesterol, isoprenoids, and neurodegeneration, supporting her commitment to advancing research in this critical area.
Department: Mechanical Engineering and Engineering Management