Dr. Elizabeth Fisher

Biography

Elizabeth Fisher completed her undergraduate degree in Physiological Sciences at St Anne's College, University of Oxford, from 1978 to 1981. She began her PhD in mouse molecular genetics in 1983 at St Mary's Hospital Medical School (Imperial College), where she focused on microdissection and microcloning of the mouse X chromosome. She was supervised by Professor Steve Brown and Dr. Mary Lyon during her PhD, which she completed in 1986. In 1987, Fisher began postdoctoral work at the Whitehead Institute, MIT, where she researched the human male sex determining factor and identified genes involved in Turner syndrome. In 1990, she returned to the UK as a Royal Society Research Fellow and started her own lab at Imperial College, focusing on the effects of aneuploidy. In 1991, she gained Wellcome Trust funding to create new ‘humanised’ mouse models for syndromes and pursue research on motor neuron degeneration, particularly in amyotrophic lateral sclerosis (ALS). Her work has included developing genetically modified mouse models and researching genes linked to neurodegeneration. She has been recognized as a Fellow of the Academy of Medical Sciences, a Member of EMBO, and a Fellow of the Royal Society of Biology. Currently, she holds a senior investigator position funded by the Wellcome Trust, sharing her expertise with collaborator Victor Tybulewicz.

Research Interests

Experience