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Elizabeth R. Wright is a Professor in the Department of Biochemistry at the University of Wisconsin–Madison. She holds the title of Henry Lardy Professor and is an affiliate of the Morgridge Institute. Her research focuses on biomolecular folding, cell structure and signaling, immunology, virology, and membrane dynamics. The Wright lab employs advanced techniques such as cryo-electron microscopy and cryo-electron tomography, aimed at understanding the architecture of complex cellular systems, including host-pathogen interactions. This research has implications for developing novel antimicrobials and therapeutics. Wright investigates bacterial motility and virulence factors, particularly the structural roles of flagellins and pili in pathogenic species. Additionally, her work delves into human cells, investigating how cellular dysfunction arises from macromolecular interactions. She is also focused on the assembly and entry mechanisms of enveloped viruses like HIV and respiratory syncytial virus. Her technological advancements in microscopy, including correlative methods, aim to bridge gaps between cryo-electron and fluorescence microscopy, pushing the boundaries of structural cell biology.
Department: Department of Computer Sciences