Dr. Emanuela Bruscia

Biography

Emanuela Bruscia received her Ph.D. in Biochemistry and Molecular Genetics from Tor Vergata University in Rome, Italy in 2002. From the start of her undergraduate studies, she dedicated her research to Cystic Fibrosis (CF) and began working in the exciting field of gene therapy. She spent years in the laboratory of Dr. Dieter Gruenert at the University of Vermont, focusing on non-viral gene therapy strategies. Dr. Bruscia began her postdoctoral training in the laboratory of Dr. Diane Krause at the Yale School of Medicine in 2002, exploring the use of bone marrow-derived cells as vehicles for gene therapy in airway and intestinal epithelia murine models of CF. In 2005, she was appointed Associate Research Scientist in the Department of Pediatrics at Yale, achieving the rank of Assistant Professor in 2010 and later being promoted to Associate Professor in 2016. Her research interest has transformed over the past decade, focusing on the role of CFTR in the immune system, particularly in macrophages. Currently, her lab investigates emerging therapeutic strategies that target aspects of CF lung disease, while also seeking to understand how the lack of CFTR impairs macrophage function.

Research Interests

Experience