Generate a tailored SOP for Dr. Emily Scott. Improve your application with a focused, well-structured draft.
Dr. Emily Scott’s research focuses on the structure-function relationship of human cytochrome P450 enzymes, which play crucial physiological roles. These enzymes are significant for the metabolism of xenobiotics, procarcinogens, and pharmaceutical agents. The Scott lab is particularly interested in inhibiting the activation of procarcinogens in vivo, such as those found in tobacco smoke, to prevent cancer initiation. Additionally, human P450 enzymes are involved in the synthesis and catabolism of important endogenous compounds, including steroid hormones, fatty acids, retinoic acid, eicosanoids, and vitamins. Recent research efforts have concentrated on understanding the biochemistry and structural biology of CYP17A1, a target for prostate cancer therapies, focusing on strategies for effective drug design. The lab employs biochemical, biophysical, and structural biology approaches, with an emphasis on X-ray crystallography and NMR spectroscopy to investigate these versatile enzymes.
Department of Electrical Engineering and Computer Science