Dr. Eran Andrechek

Biography

Eran Andrechek is a Professor in the Department of Physiology at Michigan State University, affiliated with the College of Natural Science. His research primarily focuses on the progression of human breast cancer, particularly the unique mutations that occur in individual tumors, which contribute to their heterogeneity. This intrinsic variability poses significant challenges in deciphering the mechanisms of tumor transformation and developing effective therapies. Andrechek's recent work has highlighted the importance of identifying the specific genomic signatures of individual tumors, which is crucial for tailored therapeutic approaches. His laboratory employs an integrative methodology, utilizing a combination of animal models and computational analysis of gene expression data to better understand mammary tumor development. Ongoing research projects in his lab include investigating the heterogeneity of breast cancer through mouse models, analyzing signaling pathway signatures, studying the role of E2F transcription factors in breast cancer models, and characterizing mammary gland development in the absence of E2Fs to model individualized therapies.

Research Interests

Experience