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Professor Eric Miska's research focuses on gene regulation and the role of non-coding RNAs in epigenetic inheritance and environmental conditioning. His current themes include the biology and pathology of microRNAs (miRNAs), the mechanisms of miRNA action, piRNA biology related to the germline, endo-siRNAs, and the evolution of small RNAs, specifically their role in RNA interference (RNAi) and host-pathogen interactions. Notably, his work on piRNAs identified their importance in germline genome stability and fertility, earning them the title of 'guardians of the genome.' His investigations delve into how piRNAs generated in the germline silence target genes and respond to foreign DNA or RNA, contributing to the evolution of these pathways. Miska has also explored the implications of epigenetic phenomena in human health and biological adaptation, with a keen interest in the transgenerational effects mediated by small RNAs and chromatin pathways, which maintain epigenetic inheritance across generations. His research is pivotal in understanding the mechanisms behind epigenetic inheritance, especially in relation to paramutation in animals and the memory of environmental changes.
Department of Anthropology (Social Anthropology focus). Applicants must have full training in anthropological methods.