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Eric Pamer is the Donald F. Steiner Professor of Medicine at the University of Chicago, where he conducts research on host-pathogen interactions and infectious diseases. His work focuses on the microbiome and its components, particularly the role of commensal bacteria in enhancing immune defenses through the production of antimicrobial factors. Pamer’s laboratory uses gnotobiotic mice to characterize various commensal bacteria at genomic, proteomic, and metabolomic levels, identifying mechanisms of antimicrobial resistance to reduce risks associated with highly antibiotic-resistant pathogens. He collaborates with clinical partners to study the impact of microbiota diversity on clinical outcomes, notably during allogeneic hematopoietic cell transplantation, where a loss of microbiota diversity has been shown to adversely affect patient outcomes. His research has contributed to understanding the role of microbiota composition in developing colitis and the effectiveness of immunotherapeutic approaches in cancer treatment.
Department of Philosophy