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Erika L.F. Holzbaur holds the William Maul Measey Professorship in the Department of Physiology at the Perelman School of Medicine, University of Pennsylvania. She earned her Bachelor of Science in Chemistry and History from the College of William and Mary in 1982 and her Ph.D. in Biochemistry from Pennsylvania State University in 1987. Her research focuses on microtubule-based motility, specifically the dynamics and mechanisms of cytoplasmic dynein and its activator dynactin. Holzbaur's work explores the role of these motor proteins in vesicular trafficking, microtubule organization, and development, as well as their connections to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS). The laboratory employs various techniques, including in vitro motility assays, biochemical assays, live-cell imaging, and transgenic mouse models, to study dynein/dynactin function and its implications in motor neuron health. Holzbaur has a strong commitment to understanding the intricate relationships between motor protein dynamics and cellular health.
Wharton Doctoral programs cover fields like Finance, Marketing, Management, and Operations, Information and Decisions.