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Erkang Fan is a Research Associate Professor in the Department of Biochemistry at the University of Washington. His research focuses on structure-based drug discovery for tropical diseases, including malaria, sleeping sickness, Chagas disease, leishmaniasis, cryptosporidiosis, and toxoplasmosis. He develops methodologies in organic synthesis and engages in generic protein-targeted screening activities to optimize drug solutions. His current projects involve creating inhibitors for methionyl-tRNA synthetase to treat sleeping sickness and Chagas disease, optimizing inhibitors of calcium-dependent protein kinase 1 for drug discovery in cryptosporidiosis and toxoplasmosis, and designing selective inhibitors for n-myristoyltransferase to combat Cryptosporidium infections. Through collaboration with structural biologists and medical experts, he aims to develop cost-effective therapeutics for neglected tropical diseases.
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