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Eugene B. Chang is the Martin Boyer Professor at the University of Chicago, leading a research group focused on the intricate interactions between intestinal microbes and their host. His scholarly interests encompass the microbiome, inflammation, mucosal immunity, inflammatory bowel diseases, metabolism, and nutrition. Dr. Chang's research addresses how environmental and lifestyle changes over the past century have transformed the human microbiome, contributing to the rise of 'new age' disorders such as diabetes, obesity, metabolic syndrome, cancer, and autoimmune diseases. He investigates how shifts in microbiome composition can disrupt immune and metabolic homeostasis, potentially triggering disease onset in genetically predisposed individuals. The Chang Lab employs advanced methodologies, including cultivation-dependent and independent microbial analyses and genetically modified gnotobiotic mouse models, to understand the factors influencing the selection and assembly of intestinal microbial communities. His work is pivotal in reshaping enteric microbiome for disease prevention and treatment. For more details, visit the Chang Lab website.
Department of Philosophy