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Eva Bertosin is an Assistant Professor in the Department of Biomolecular Sciences at Utrecht University. Her research interests focus on membrane biochemistry and biophysics, specifically the complex interactions within protein systems that enable cells to perform tasks with remarkable precision and efficiency. Her work revolves around understanding how chaperones, such as bacterial GroEL/ES and eukaryotic TRiC, utilize allosteric mechanisms and intricate conformational changes to aid in the folding of essential proteins. Eva aims to re-engineer these natural systems from the ground up using DNA origami, a powerful technique for constructing complex structures with customizable dynamics and switchable conformations. This bottom-up engineering approach provides comprehensive control over structural transitions and allosteric coupling in artificial systems, offering profound insights into protein folding and chaperone functions and paving the way for designing nanostructures endowed with novel complex functions.
Department of Psychology