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Evan Macosko is an Associate Professor in Neurobiology at Harvard University, affiliated with Massachusetts General Hospital. He specializes in cellular specialization in the nervous system, focusing on cellular diversity within the mammalian brain. His research addresses the pathogenic mechanisms underlying neuropsychiatric diseases that remain poorly understood. Dr. Macosko's work characterizes specific cell populations in disease-relevant contexts, providing insights into pathogenic processes and leading to novel disease models and potential treatments. He has developed technology, known as Drop-seq, which facilitates the transcriptional profiling of tens of thousands of individual cells in a cost-effective manner. His lab is currently engaged in constructing comprehensive cell-type atlases of major tissues in the mouse brain while investigating how cell types transcriptionally vary across genetic and environmental contexts. His research aims to explore exciting intersections of molecular techniques, cellular neuroscience, genomics, and computational biology, particularly in the context of understanding and treating complex brain diseases.
Administered by the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences (GSAS).