Dr. Evgueni Ivakine

Associate Professor

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Biography

Evgueni (Zhenya) Ivakine is an Associate Professor in Molecular Genetics at SickKids. His research focuses on understanding disease pathogenesis and developing next-generation genetic medicines for the treatment of rare inherited disorders. Ivakine employs advanced techniques like saturation prime editing to predict disease risk at single nucleotide resolution and creates cellular and animal models to study disease mechanisms. His work includes developing and testing treatments for genetic conditions, particularly neurodevelopmental and neurodegenerative diseases such as Niemann-Pick disease type C and Tay-Sachs disease. Additionally, he utilizes genome engineering tools, including CRISPR-Cas9, prime editing, and base editing, to study mutations that lead to genetic diseases and to explore innovative therapeutic strategies at the DNA level.

Research Interests

Genetic Models Disease & Development Molecular Medicine & Human Genetics Functional Genomics & Proteomics Cancer CRISPR-Cas9 Genome Engineering Disease Models Functional Genomics Systems Biology Genome Analysis Sequencing Mouse Models Neurodegeneration Neurodevelopment Rare Diseases Technology Development

Experience

Associate Professor

— Present

SickKids • Toronto, Canada

Conducts research in molecular genetics focused on disease pathogenesis and genetic medicine.

Courses

MMG3006Y: Genetic Models Disease & Development MGY250: Molecular Medicine & Human Genetics Functional Genomics & Proteomics

Requirements for University of Toronto

Master Program
Requirements
GPA Requirement
Required:3.3
IELTS
Listening
Required:6.5
Reading
Required:6.5
Writing
Required:6.5
Speaking
Required:6.5
Overall
Required:7
TOEFL
Listening
Required:22
Reading
Required:22
Writing
Required:22
Speaking
Required:22
Total
Required:93
Prerequisites
Appropriate four-year bachelor's degree Background in sociological theory and statistics preferred
Application Checklist
  • Transcripts
  • Two letters of reference
  • Statement of intent
  • Writing sample
  • Curriculum Vitae
Specialization Notes

Department of Sociology