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Dr. Fanxin Long is a Professor in the Department of Orthopaedic Surgery at the University of Pennsylvania. His research focuses on understanding the fundamental mechanisms underlying normal skeletal development and the pathophysiology of bone disorders. He aims to discover key steps in the molecular and metabolic regulation of skeletal cell differentiation and function in hopes of uncovering therapeutic targets for treating skeletal diseases. His lab has identified key roles for developmental signals, such as Hedgehog, Wnt, Notch, and BMP, in regulating skeletal development and homeostasis through mouse genetic studies. Additionally, Dr. Long's research has highlighted the cellular metabolic disruptions contributing to osteoarthritis and diabetic osteopenia. He employs single-cell sequencing technology and genetic lineage-tracing in functional studies to identify skeletal stem/progenitor cells and examines their contributions to bone maintenance and pathology.
Wharton Doctoral programs cover fields like Finance, Marketing, Management, and Operations, Information and Decisions.