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Fernando De La Cuesta is a Marie Curie Research Fellow in the Centre for Cardiovascular Science at the University of Edinburgh. His research focuses on the role of extracellular vesicles in pulmonary hypertension, particularly studying the cell-to-cell communication between human smooth muscle cells and endothelial cells. He is investigating the relevance of vascular injury in these conditions and the significance of long non-coding RNA crosstalk in this context. His work involves imaging EV transfer in vascular cells and optimizing methodologies based on Cre-loxP recombination to examine fluorescent color switches in cells upon EV uptake. Furthermore, he analyzes RNA cargoes present in extracellular vesicles using RNA-Seq to unveil their biological relevance in pulmonary arterial hypertension. Fernando is involved in collaborative projects that utilize proteomics and gene therapy techniques, including viral vectors and Single-Cell RNA-Seq.
University of Edinburgh • Edinburgh, GB
Conducting research on the role of extracellular vesicles in pulmonary arterial hypertension.
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