Professor Dr. Francesca Paradisi

Biography

Francesca Paradisi is a Professor of Sustainable Pharmaceutical Chemistry at the University of Bern, Switzerland, where she leads a research group focused on the development of alternative biocatalysts for synthetic industrial applications. Her research primarily involves the discovery and characterization of enzymes from extremophilic organisms, particularly salt-adapted microbes capable of withstanding high salt concentrations. Paradisi's work on enzymatic properties includes the adaptation of organisms to enhance their stability in organic solvents and broad substrate scope. Her current projects explore various enzymes, including oxido-reductases, transaminases, and hydrolases, with the aim to improve enzymatic stability through tailored immobilization strategies for batch and flow systems. Additionally, Paradisi collaborates with a network of researchers across Europe, targeting the assembly of semi-synthetic enzymes to boost biocatalytic properties, while her lab also focuses on the incorporation of non-natural amino acids to create peptidomimetics with enhanced anti-cancer activity.

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Experience

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