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Francesca Paradisi is a Professor of Sustainable Pharmaceutical Chemistry at the University of Bern, Switzerland, where she leads a research group focused on the development of alternative biocatalysts for synthetic industrial applications. Her research primarily involves the discovery and characterization of enzymes from extremophilic organisms, particularly salt-adapted microbes capable of withstanding high salt concentrations. Paradisi's work on enzymatic properties includes the adaptation of organisms to enhance their stability in organic solvents and broad substrate scope. Her current projects explore various enzymes, including oxido-reductases, transaminases, and hydrolases, with the aim to improve enzymatic stability through tailored immobilization strategies for batch and flow systems. Additionally, Paradisi collaborates with a network of researchers across Europe, targeting the assembly of semi-synthetic enzymes to boost biocatalytic properties, while her lab also focuses on the incorporation of non-natural amino acids to create peptidomimetics with enhanced anti-cancer activity.
University of Bern • Bern, CH
Leads research in Sustainable Pharmaceutical Chemistry.
University of Nottingham & Adjunct Professor • University College Dublin, IE
Conducted research and teaching in the field of biocatalysis.
University College Dublin, IE • Dublin, IE
Taught courses and guided research in organic and medicinal chemistry.
University College Dublin, IE • Dublin, IE
Instructed undergraduate and postgraduate students in chemistry subjects.
University College Dublin, IE • Dublin, IE
Conducted research in synthetic organic chemistry.
Part of the Swiss Joint Master in Computer Science (Bern, Fribourg, Neuchâtel).