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The Host-Microbe Interaction lab is interested in understanding the interplay between established bacteria and host infection. The research is currently focusing on the enteropathogen Shigella flexneri, which uses the Type Three Secretion Apparatus (T3SA) to inject proteins into human intestinal cells. The main interests are threefold: 1) the functioning and regulation of T3SA; 2) bacterial strategies for hijacking biological processes of the host; and 3) bacterial-host adaptation during infection. The long-term objective is to identify novel therapeutic avenues to treat infectious diseases.
Department of History