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Francois Spitz is a Professor in the Biological Sciences Division at the University of Chicago, specializing in Human Genetics. His research primarily focuses on understanding the architecture of genomes and how they contribute to the specificity and robustness of gene expression programs that govern embryonic development and cell differentiation. Leveraging the extensive complexity of vertebrate genomes, which contain numerous regulatory elements influencing gene expression from considerable distances, his work aims to elucidate the folding of the genome into specific domains and dynamic structures that convert widely dispersed information into highly specific regulatory ensembles. Furthermore, he investigates how perturbations such as chromosomal rearrangements can lead to developmental and oncogenic pathologies and has contributed to studies regarding animal evolution.
Department of Philosophy