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Ganesan Vaidyanathan is a Professor Emeritus at the Fitzpatrick Institute Photonics of Duke University, specializing in the field of Radiology. His research primarily focuses on the development of radiopharmaceuticals for oncologic applications. He has been involved in several significant projects, including the design of new methods for radiohalogenating antibody variants and the development of advanced residualizing agents for radiohalogenation of internalizing monoclonal antibodies. His work also includes the creation of fluorine-18 labeled residualizing agents and the pre-targeting approach using bioorthogonal chemistry for in vivo labeling of antibodies and nanobodies. Additionally, Vaidyanathan has investigated MIBG analogs for PET imaging in neuroendocrine tumors and the noninvasive imaging of alkylguanine-DNA alkyltransferase (AGT), a key protein responsible for drug resistance in alkylator chemotherapy. His contributions to targeting prostate cancer therapy through the development of At-211 labeled inhibitors of Prostate-specific membrane antigen further underscore his expertise in the field.
Department of Biomedical Engineering (MS program)