Dr. Gary Bader

Biography

Gary Bader is a Professor at the Donnelly Centre, University of Toronto, and an international leader in the field of Computational Biology. Bader's lab employs molecular interaction and pathway genomics data to achieve causal mechanistic understanding of normal and disease phenotypes. His research has led to the development of novel computational approaches that combine molecular interaction pathways and ‘omics data to create clinically predictive models for identifying therapeutically targetable pathways. Notably, his work identified a histone methylation inhibitor as a therapeutic candidate for pediatric ependymoma, a common childhood brain cancer, in collaboration with Michael Taylor from SickKids. Additionally, Bader's lab is focused on creating computational methods informed by ecosystem theory to understand how tissue functions via cell-cell interactions, growth, internal mechanisms, and causal relationships, contributing to comprehension of development, cancer, and regenerative wound healing processes.

Research Interests