Dr. Genevieve Stein O'brien

Biography

Genevieve Stein-O'Brien is an Assistant Professor in the Solomon H Snyder Department of Neuroscience and Neurology at Johns Hopkins University. She is also the Associate Director of the JHU Single-cell Training Analysis Center and a Terkowitz Family Rising Professor at the Brain Science Institute. Her research focuses on single-cell gene expression profiling to understand the intrinsic and extrinsic molecular features of cells within the central nervous system. The lab aims to integrate computational and experimental methods to explore how single-cell molecular programs interact with external physiological contexts, particularly in relation to neurophysiology and human diseases such as Amyotrophic Lateral Sclerosis and Frontal Temporal Dementia. Stein-O’Brien's work emphasizes the importance of reproducibility in research and collaboration with experts in human genetics, aging, and cancer to explore variations in phenotypes and genotypes.

Research Interests

Experience