Professor Dr. Geoffrey Greene

Biography

Geoffrey Greene is the Virginia D. K. Ludwig Professor at the University of Chicago, specializing in cancer research with a focus on hormone receptors. His research interests include the androgen receptor, breast and prostate cancer, and nuclear receptor signaling mechanisms. Greene’s laboratory has significant expertise in developing and characterizing selective estrogen receptor modulators (SERMs) and investigating their therapeutic potential in hormone-dependent cancers. His studies have contributed to understanding the structural basis for hormone-receptor interactions and the role of receptor mutations in endocrine-resistance in breast cancer. Greene has published extensively on these topics, including works on the use of cell-derived explant patient-derived xenograft models to study breast cancer progression and develop treatment combinations targeting multiple steroid receptors. He has received several prestigious awards for his contributions to cancer research and continues to be an influential figure in the field, focusing on new therapeutic strategies to combat resistant cancer types.

Research Interests

Awards