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George M. Burslem is an Assistant Professor in the Department of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania. His research expertise lies in the development of novel chemical approaches to modulate lysine post-translational modifications. This includes synthetic protein engineering techniques to understand lysine modifications and chemical biology methods to modulate these processes for potential therapeutic applications. Burslem's laboratory focuses on the significance of post-translational modifications (PTMs) in protein function and their roles in cellular signaling and processes such as protein stability and gene expression regulation, particularly in the context of haematological malignancies. He employs a multidisciplinary approach that combines synthetic chemistry, biochemistry, and cell biology to investigate these biological systems, with an emphasis on cancer biology. His lab is actively seeking rotation students and postdoctoral fellows to contribute to their ongoing research projects.
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