Dr. George Daley

Biography

George Quentin Daley, M.D., Ph.D., is the Dean at the Faculty of Medicine and a Professor of Biological Chemistry and Molecular Pharmacology. His research lab focuses on stem cell biology, particularly on the hematopoietic differentiation of human and mouse pluripotent stem cells (embryonic stem cells and induced pluripotent stem cells). His work emphasizes epigenetic reprogramming and germ cell development, exploring the overlaps between germ cells, stem cells, and cancer. Daley's laboratory aims to define genetic programs necessary for the formation of hematopoietic stem cells and the mechanisms underlying directed differentiation from pluripotent cells. He employs various techniques, including somatic cell nuclear transfer and direct reprogramming, to develop genetically defined stem cells for therapeutic models. His studies also investigate the Lin28/let-7 axis and its implications for developmental timing and the balance between self-renewal and differentiation in stem cell populations, which is vital for understanding tumorigenesis, particularly concerning germ cells and blood.

Research Interests

Experience