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Goedele Maertens is a Professor at Imperial College London, specializing in Retrovirology within the Department of Infectious Disease. Her research focuses on the interactions between retroviruses and host cellular machinery, particularly studying the integration of retroviral DNA into host genomes. One of the primary areas of her work is the investigation of human T-cell lymphotropic virus type 1 (HTLV-1), which is associated with various severe health conditions including adult T-cell leukemia/lymphoma and myelopathy. Maertens' research has profound implications for understanding the persistence of viral infections and the development of effective treatments. Her laboratory is currently exploring the mechanisms by which PT2A-B56 modulates HTLV-1 integration and seeking novel therapeutic interventions. She has published extensively on retroviral integrases and their role in integration site targeting, contributing to the broader understanding of viral vectorization and integration mechanisms.
Imperial College London • United Kingdom
Imperial College London • United Kingdom
Imperial College London • United Kingdom
Specialisms available in Materials for the Energy Transition or Theory and Simulation of Materials.