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Gokhan Mutlu is a Professor of Medicine and Chief of the Section of Pulmonary Critical Care Medicine at the University of Chicago. His extensive research focuses on the mechanisms of acute lung injury and pulmonary fibrosis. In his lab, he investigates the roles of macrophage and fibroblast metabolism, particularly their mitochondrial function in the pathogenesis of these conditions. The laboratory is well-versed in both in vitro cell-based methods and in vivo models that study acute lung injury, including influences of influenza, LPS, bacterial pneumonia, and particulate matter as well as pulmonary fibrosis induced by bleomycin. Mutlu is also the principal investigator and director of the NIH T32 Research training in respiratory biology, leading various projects that analyze the impacts of intermittent hypoxia and DNA methylation in mitochondrial reactive oxygen species dynamics. With a robust background, he contributes significantly to the understanding of respiratory health.
Department of Philosophy