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Graeme Mason develops experimental models and methods for studying brain metabolism utilizing 1H, 2H, and 13C Nuclear Magnetic Resonance (NMR) and Mass Spectrometry in conjunction with 13C isotopic labeling in vivo and cell preparations. His research began during graduate studies at Yale, utilizing a rat model for the experimental determination of brain glucose transport kinetics, energetics, and neurotransmitter metabolism. Further training at the University of Alabama at Birmingham involved guiding a team in 13C-labeling studies of the human brain using a whole-body MR system. Mason's ongoing research focuses on metabolism and neurotransmission in the brain, examining the effects of psychiatric, neurological, and metabolic conditions. He investigates healthy subjects and patients to explore the relationships between GABA, glutamate, and glutamine concentrations and the rates of their synthesis and release in the brain, paying particular attention to the effects of alcohol use.
Yale School of Medicine • New Haven, CT
Director of Metabolic Modeling and Psychiatric MRS, Radiology & Biomedical Imaging. Chair of the Magnetic Resonance Research Center Protocol Review Committee.
Administered via the Graduate School of Arts and Sciences (GSAS). GRE General is optional for PhD.