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Professor Graham E. Holder is the Hong-Leong Professor at the Department of Ophthalmology in the Yong Loo Lin School of Medicine at the National University of Singapore. His research primarily focuses on clinical electrophysiology and vision, centering on how these areas contribute to disease management in the visual system. He has extensive experience at Moorfields Eye Hospital in London, where he directed the electrophysiology department for 22 years. Professor Holder developed crucial methodologies for differentiating between visual acuity loss caused by optic nerve diseases and macular diseases through the use of pattern electroretinograms (PERG). His published work emphasizes the importance of structure-function relationships and electrophysiological data in the accurate diagnosis and management of inherited retinal diseases. He has led significant gene therapy trials and has contributed to numerous studies linking genotype-phenotype relationships in retinal diseases. Additionally, he collaborates with various international research institutions, focusing on advancements in electrophysiology and imaging techniques, which enhance diagnostic accuracy and treatment efficacy.
Tan Tock Seng Hospital • Singapore
Guest faculty member, providing expertise in ocular electrophysiology.
Singapore National Eye Centre • Singapore
Consulting on complex cases involving retinal and optic nerve diseases.
Institute of Ophthalmology, University College London • UK
Contributing to research and education in ophthalmic science.
Moorfields Eye Hospital • London, UK
Oversaw clinical services in electrophysiology and led various clinical studies.
Department of Economics