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Dr. Guo-li Ming is a prominent researcher at the Perelman School of Medicine at the University of Pennsylvania, holding the title of Perelman Professor in the Department of Neuroscience. He specializes in neurobiology with a keen focus on understanding the molecular mechanisms underlying neurodevelopment and the dysregulation contributing to developmental neurological disorders. His laboratory employs a range of experimental approaches that include molecular biology, biochemistry, mouse genetics, imaging, electrophysiology, and optogenetic manipulations to explore vital topics such as neuronal migration, axon and dendritic development, synapse formation, circuitry integration, and the functional regeneration of mature neurons. Additionally, his research utilizes genetically modified mouse systems alongside patient-derived induced pluripotent stem cell (iPSC) model systems to deepen the understanding of these complex processes.
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