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Dr. Hannah Clarke investigates the neurochemical basis of negative emotional behavior and its implications for psychiatric disorders. Her research focuses on the ability to regulate emotions in response to stimuli, which is crucial for appropriate interactions within an environment. Abnormal emotional regulation can lead to significant issues evident in conditions such as depression and anxiety disorders, largely stemming from cognitive biases towards emotive stimuli, with failures in integrating behavioral and physiological responses. The role of specific brain regions, including the amygdala, hippocampus, and medial prefrontal cortex, in these emotional responses remains poorly understood. Dr. Clarke's research aims to elucidate how these brain areas communicate and regulate emotion, using neuroimaging techniques alongside neurochemical manipulations and monitoring of cardiovascular responses. Her work incorporates genetic screening and examines proteins involved in emotional responsiveness, such as BDNF and cortisol, to better understand the etiology of psychiatric disorders and to foster developments in targeted pharmacotherapy.
Department of Physiology, Development Neuroscience, University of Cambridge • Cambridge
Standard postgraduate requirements for Department of Politics and International Studies (POLIS) and related humanities departments.