Dr. Haribabu Arthanari

Biography

Haribabu Arthanari is an Associate Professor in the Biological Chemistry and Molecular Pharmacology departments. His research focuses on protein-protein interactions (PPIs) as a therapeutic intervention point, exploring the distinct structural landscapes that can be targeted for high specificity. The Arthanari lab employs structure-guided approaches to characterize and validate interactions in disease models, using a combination of techniques including NMR spectroscopy, high throughput screening, and biophysical cell-based assays to map interaction hotspots and improve the understanding of the molecular mechanisms involved. His current research interests include the interactions of transcription factors with the general transcriptional machinery and translation initiation machinery, particularly in the context of cancer. He is dedicated to developing novel NMR methods that expand the capabilities of NMR techniques to analyze larger complex systems, as well as uncovering secrets of the disordered regions of the human proteome, often referred to as the 'Dark Proteome'.

Research Interests