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Dr. Hening Lin is the James Karen Frank Family Professor in the Department of Medicine at the University of Chicago. His research focuses on the function and regulation of therapeutic targeting enzymes that control protein post-translational modifications (PTMs). With the human genome sequenced, major challenges remain in understanding protein function in biology and medicine. Dr. Lin's work emphasizes elucidating the role of proteins and how their activity is regulated by cellular stress signaling cues. His laboratory is dedicated to investigating the function of regulatory PTM enzymes and developing small molecule inhibitors to advance novel therapeutics for human diseases, including cancer, autoimmune disorders, and neurodegenerative conditions. Dr. Lin has an extensive publication record, contributing to the understanding of myristoylation, palmitoylation, and the modulation of various cell signaling pathways.
Department of Philosophy