Dr. Henry Binder

Biography

Dr. Henry J. Binder's research career focused on the regulation of colonic electrolyte transport and the pathophysiology of diarrhea, contributing significantly to the development of new treatment approaches for this condition. His primary research involved in vitro studies to dissect cellular mechanisms of transport for sodium, chloride, potassium, and bicarbonate, alongside exploring short-chain fatty acid transport. He was supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) for 37 years. In recent years, he concentrated on establishing a major modification of oral rehydration solutions (ORS) based on laboratory studies that revealed butyrate-stimulated sodium absorption in the colon, which is cyclic AMP-insensitive. His innovations in ORS, aimed at increasing uptake and adapting improved formulations, have implications for enhancing treatment in resistant starch cases. Dr. Binder has written extensively on topics including ion transport and digestive system diseases, collaborating frequently with other researchers in these fields.

Research Interests